Peptide Database

Peptide NameSLAY-screened peptide P4032

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC87H143N25O34S

DescriptionStandard

        TTPTGRSTDVKTGEYVSNAM
    

Molecular Weight2115.28 Da

Isoelectric Point (pI)5.73

Net Charge (pH 7.0)-0.60

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0300

GRAVY Index-0.78

Hydrophobic Moment 0.41

Boman Index-0.12

Instability Index17.77

Aliphatic Index 34.00

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 974.88

LogP -15.09

H-bond Donors 35.0

H-bond Acceptors 35.0

Rotatable Bonds 67.0

Heavy Atoms 147.0

Ring Count 2.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243806 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/