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MYP_102951
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Basic Information
Neurokinin A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Neurological / Signaling ▸ Tachykinin peptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
10 amino acids
C50H79N13O15S
Standard
Sequence
HKTDSFVGLM
Physicochemical Analysis
1134.31 Da
6.74
-0.15
-0.41
-0.0153
0.02
0.21
0.14
43.45
68.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
457.68
-3.97
16.0
17.0
37.0
79.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0276558 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 60.0%, E 0.0%, T 20.0%, C 20.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Cell-Cell Communication Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0288410 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID18603306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18603306/
RECORD: Rec_0290656 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Neurokinin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Vasoactive Vasodilator Growth regulation Development regulation Receptor modulation
Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Neurokinin A (Homo sapiens): PMID 3038549 PMID3038549 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3038549/
RECORD: Rec_0296195 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Neuropeptide Anti-Gram-positive Anti-Gram-negative
Lactobacillus acidophilus NCTC 1723
500 μg/mL
MIC
PMID18603306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18603306/
RECORD: Rec_0325268 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Neuropeptide Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
500 μg/mL
MIC
PMID18603306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18603306/
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