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MYP_102951
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Basic Information
Neurokinin A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Neurological / Signaling ▸ Tachykinin peptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
10 amino acids
C50H79N13O15S
Standard
Sequence
HKTDSFVGLM
Physicochemical Analysis
1134.31 Da
6.74
-0.15
-0.41
-0.0153
0.02
0.21
0.14
43.45
68.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
457.68
-3.97
16.0
17.0
37.0
79.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0123122 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis
PMID18603306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18603306/
RECORD: Rec_0135155 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Streptococcus mutans
PMID18603306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18603306/
RECORD: Rec_0203261 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Neuropeptide Anti-Gram-positive Anti-Gram-negative
Streptococcus mutans NCTC 10449
500 μg/mL
MIC
PMID18603306 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18603306/
RECORD: Rec_0212187 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Neurokinin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Growth regulation Development regulation Receptor modulation Immunomodulatory
Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
RECORD: Rec_0224003 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]; Bos taurus [Animal]; Homo sapiens [Animal]; Mesocricetus auratus [Animal]; Mus musculus [Animal]; Oryctolagus cuniculus [Animal]; Rattus norvegicus [Animal]; Gallus gallus [Animal]
Tachykinin
9823, 9913, 9606, 10090, 9986, 10116, 9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
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