Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC507H807N135O152S10

DescriptionStandard

        MSVMKPYLMTISILLILVPKTPGDLFRSYYGNSQEPWIPCQLYHGMCRNTCRNNEIQYLTCPSDQKCCLKLSVKVARPNNVKDYDSDSNLSVTNISSYSKI
    

Molecular Weight11546.29 Da

Isoelectric Point (pI)8.77

Net Charge (pH 7.0)3.53

Net Charge (pH 7.4) 3.14

Charge Density (pH 7.0) 0.0349

GRAVY Index-0.28

Hydrophobic Moment 0.63

Boman Index-0.01

Instability Index43.23

Aliphatic Index 83.86

Aromaticity 0.0891

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16305.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4649.70

LogP -47.85

H-bond Donors 165.0

H-bond Acceptors 167.0

Rotatable Bonds 377.0

Heavy Atoms 804.0

Ring Count 18.0

Amide Bonds 112.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148675 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera tigris altaica [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence