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MYP_102928
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Basic Information
P1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anthelminthic
Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C118H197N35O23S2
Standard
Sequence
KSLRPRCWIKIKFRCKSLKF
Physicochemical Analysis
2538.18 Da
11.13
7.74
7.50
0.3868
-0.49
0.43
-0.33
19.85
78.00
0.1500
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
979.48
-5.21
39.0
33.0
88.0
178.0
5.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0326657 VERIFIED: YES
Provenance & Taxonomy
Erebia neriene [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0346748 VERIFIED: YES
Provenance & Taxonomy
Picea sitchensis [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Escherichia coli
18.75 μg/mL
MIC
RECORD: Rec_0348250 VERIFIED: YES
Provenance & Taxonomy
Picea sitchensis [Plant]
3332
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Nematocidal Anthelmintic Anti-Gram-negative
Pseudomonas aeruginosa
9.38 μg/mL
MIC
PMID21644248 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21644248/
RECORD: Rec_0368228 VERIFIED: YES
Provenance & Taxonomy
Picea sitchensis [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-15
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC 43300
9.38 μg/mL
MIC
PMID21644248 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21644248/
RECORD: Rec_0371124 VERIFIED: YES
Provenance & Taxonomy
Picea sitchensis [Plant]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID21644248 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21644248/
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