Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC344H550N90O92S9

DescriptionStandard

        MKTGLFLFAALFFLAPAKNEFFDDKCYQLKGKCMRHCQKNEELVALCQKSLKCCLTLQPCGKIRLDD
    

Molecular Weight7707.18 Da

Isoelectric Point (pI)8.74

Net Charge (pH 7.0)3.52

Net Charge (pH 7.4) 3.13

Charge Density (pH 7.0) 0.0526

GRAVY Index-0.05

Hydrophobic Moment 0.51

Boman Index-0.01

Instability Index26.02

Aliphatic Index 81.64

Aromaticity 0.1045

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2953.56

LogP -22.26

H-bond Donors 106.0

H-bond Acceptors 106.0

Rotatable Bonds 265.0

Heavy Atoms 535.0

Ring Count 10.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037928 VERIFIED: NO

Provenance & Taxonomy

OrganismIctidomys tridecemlineatus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence