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MYP_102890
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Basic Information
EK0-2, HCoV-OC43-HR2P [Q13E,N17K,R18K,Q20E,V25K,N27,Q28E,D35E]
Antiviral
Standard
36 amino acids
C195H315N43O64S
Standard
Sequence
SLDYINVTFLDLEDEMKKLEEAIKKLEESYINLKEI
Physicochemical Analysis
4317.90 Da
4.36
-5.52
-5.76
-0.1534
-0.41
0.75
-0.04
35.52
119.17
0.0833
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1772.25
-10.37
59.0
60.0
155.0
303.0
3.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0224781 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HCoV-NL63
PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0258941 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HCoV-229E
PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0305762 VERIFIED: YES
Provenance & Taxonomy
Human coronavirus OC43 [Virus]
HR2-derived fusion inhibitor
31631
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human coronavirus NL63
0.63 μM
IC50
PaperA pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0322615 VERIFIED: YES
Provenance & Taxonomy
Human coronavirus OC43 [Virus]
HR2-derived fusion inhibitor
31631
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human coronavirus OC43
0.53 μM
IC50
PaperA pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0323058 VERIFIED: YES
Provenance & Taxonomy
Human coronavirus OC43 [Virus]
HR2-derived fusion inhibitor
31631
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human coronavirus 229E
0.22 μM
IC50
PaperA pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
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