Peptide Database

Peptide NameProgonadoliberin-2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC320H504N96O93S2

DescriptionStandard

        QHWSHGWYPGGKRELDSFTTSEISEGIKLCEAEGCSYLRPQRRNILKNVILDALAREFQKRK
    

Molecular Weight7248.14 Da

Isoelectric Point (pI)9.14

Net Charge (pH 7.0)2.93

Net Charge (pH 7.4) 2.57

Charge Density (pH 7.0) 0.0472

GRAVY Index-0.85

Hydrophobic Moment 0.73

Boman Index-0.20

Instability Index63.62

Aliphatic Index 72.42

Aromaticity 0.0968

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3107.20

LogP -30.43

H-bond Donors 112.0

H-bond Acceptors 100.0

Rotatable Bonds 246.0

Heavy Atoms 511.0

Ring Count 12.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012901 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus mykiss [Animal]

FamilyProgonadoliberin

Tax ID8022

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour