Peptide Database

Peptide NamePyocin large subunit

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length420 amino acids

Chemical FormulaC1985H3125N577O609S16

DescriptionStandard

        MAKGYILHMYDPTTCGGRILDGAPNRRTNGTSIARMGDRVSCGKDGNIYRIVGGIGWIKTDGRLVAGSLHSFSSCPCNAKIIPQITVQAYDSLSESRMFSPVVATTPSTVVSSHLSPVVSRAALLPVPVFAKSRERGTGNTDAGKQQEPHTNFAEMGLFRAAPAADAAIDFDAPQHAQTAKKKPPAPEDISKPKKRSALYKWLNGNHEEIQYQAAVAAAASASRAQTATAGAGVLEQVAGRFATYGTWAVQGTEIAAGGVGASVAGFLVGMMPGKLNEGEQDFIDRMRLAQMREAPSRVRFTWEDSSNGHPVPHGYHTPPGKDMVRVRKMEWDRRYEAYTFATEEEKSVTIIWTPDHSDVNTPSNTGNQTPPRLSGAIPVDPLPDDSRIATTTTPAPDEKSFADYILILQCQTSRRFISI
    

Molecular Weight45329.59 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)4.37

Net Charge (pH 7.4) 3.49

Charge Density (pH 7.0) 0.0104

GRAVY Index-0.39

Hydrophobic Moment 0.75

Boman Index-0.01

Instability Index40.67

Aliphatic Index 68.62

Aromaticity 0.0714

Extinction Coeff. Reduced 49390.00

Extinction Coeff. Oxidized 49640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028274 VERIFIED: YES

Provenance & Taxonomy

OrganismLeclercia adecarboxylata [Bacterium]

FamilyPyocin

Tax ID911008

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)