Peptide Database

Peptide NameBrain natriuretic peptide

Function Ontology

Antimicrobial

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC209H356N70O63S2

DescriptionStandard

        SQGSTLRVQQRPQNSKVTHISSCFGHKIDRIGSVSRLGCNALKLL
    

Molecular Weight4921.62 Da

Isoelectric Point (pI)10.95

Net Charge (pH 7.0)5.61

Net Charge (pH 7.4) 5.27

Charge Density (pH 7.0) 0.1247

GRAVY Index-0.36

Hydrophobic Moment 0.65

Boman Index-0.12

Instability Index50.90

Aliphatic Index 90.89

Aromaticity 0.0222

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2195.86

LogP -29.41

H-bond Donors 80.0

H-bond Acceptors 73.0

Rotatable Bonds 170.0

Heavy Atoms 344.0

Ring Count 4.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017024 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBrain natriuretic peptide

Tax ID10090

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide23-39

Bio-Activity Profile

Function

Antimicrobial Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Growth regulation Development regulation Receptor modulation Immunomodulatory

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0237106 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyNatriuretic peptide

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide23-39

Bio-Activity Profile

Function

Hormone Cardiovascular

RECORD: Rec_0305737 VERIFIED: NO

Provenance & Taxonomy

Organismmus musculus [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide23-39

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0391708 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 33.3%, C 66.7% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication