Peptide Database

Peptide NameLeptin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC709H1160N190O220S5

DescriptionStandard

        VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC
    

Molecular Weight16026.26 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-2.92

Net Charge (pH 7.4) -3.39

Charge Density (pH 7.0) -0.0200

GRAVY Index0.04

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index44.16

Aliphatic Index 113.42

Aromaticity 0.0411

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6581.57

LogP -67.93

H-bond Donors 227.0

H-bond Acceptors 226.0

Rotatable Bonds 538.0

Heavy Atoms 1124.0

Ring Count 18.0

Amide Bonds 160.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0235823 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familyleptin family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide96-146

Bio-Activity Profile

Function

Hormone leptin family Angiogenic

RECORD: Rec_0369827 VERIFIED: NO