Peptide Database

Peptide NameNeuromedin-B-32

Function Ontology

Antiviral

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC164H254N52O43S

DescriptionStandard

        APLSWDLPEPRSRASKIRVHSRGNLWATGHFM
    

Molecular Weight3674.16 Da

Isoelectric Point (pI)11.54

Net Charge (pH 7.0)2.97

Net Charge (pH 7.4) 2.68

Charge Density (pH 7.0) 0.0929

GRAVY Index-0.62

Hydrophobic Moment 0.37

Boman Index-0.10

Instability Index45.44

Aliphatic Index 67.19

Aromaticity 0.0938

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1520.45

LogP -14.77

H-bond Donors 55.0

H-bond Acceptors 49.0

Rotatable Bonds 114.0

Heavy Atoms 260.0

Ring Count 10.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040418 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBombesin/neuromedin-B/ranatensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Hormone

RECORD: Rec_0054792 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 40.6%, T 25.0%, C 34.4% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0321366 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNeuromedin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antiviral Hormone Endocrine Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation Immunomodulatory Pruriceptive

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour