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MYP_102830
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Basic Information
Brevinin-2RTb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
33 amino acids
C147H255N39O46S2
Standard
Sequence
GILDTLKEFGKTAAKGIAQSLLSTASCKLAKTC
Physicochemical Analysis
3368.96 Da
9.24
2.74
2.50
0.0830
0.25
0.66
0.11
18.74
97.88
0.0303
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1383.92
-15.92
51.0
51.0
118.0
234.0
1.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0219411 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Psychrobacter faecalis
12.5 μg/mL
MIC
RECORD: Rec_0228746 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
rabbit red blood cells
400 μg/mL
LD50
PMID22100518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100518/
RECORD: Rec_0233850 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID22100518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100518/
RECORD: Rec_0239833 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus carnosus KHS
100 μg/mL
MIC
PMID22100518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100518/
RECORD: Rec_0280627 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC2592
50 μg/mL
MIC
PMID22100518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100518/
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