Peptide Database

Peptide NameLL12b

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC72H138N16O13

DescriptionStandard

        LLKKLLKLLLKL
    

Molecular Weight1435.97 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.3130

GRAVY Index1.23

Hydrophobic Moment 0.75

Boman Index0.21

Instability Index-33.28

Aliphatic Index 260.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 487.50

LogP 2.62

H-bond Donors 17.0

H-bond Acceptors 17.0

Rotatable Bonds 55.0

Heavy Atoms 101.0

Ring Count 0.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0358400 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

Activity87 μM

MethodMIC

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