Peptide Database

Peptide NameSubstitution mutant of Kunitzin-OS

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC90H141N23O19S2

DescriptionStandard

        AAKIILNPKFRCFAAFC
    

Molecular Weight1913.36 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)2.77

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1632

GRAVY Index0.94

Hydrophobic Moment 0.38

Boman Index0.25

Instability Index14.05

Aliphatic Index 92.35

Aromaticity 0.1765

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 677.16

LogP -3.14

H-bond Donors 25.0

H-bond Acceptors 24.0

Rotatable Bonds 60.0

Heavy Atoms 134.0

Ring Count 4.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316888 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli

Activity160 μM

MethodMIC