MYP_102819
E2EM15W-S2
Antimicrobial
Antimicrobial
▸
Antibacterial
Standard
15 amino acids
C81H131N21O20
Standard
TLKQFAKGWGKDLVK
1719.04 Da
10.00
2.40
2.20
0.1597
-0.57
0.65
-0.07
2.48
78.00
0.1333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
691.21
-4.18
24.0
23.0
60.0
122.0
3.0
15.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0080883
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Escherichia coli
100 μg/mL
MIC
RECORD: Rec_0156802
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Salmonella typhimurium
>200 μg/mL
MIC
RECORD: Rec_0167101
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Pseudomonas aeruginosa
200 μg/mL
MIC
RECORD: Rec_0181158
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Proteus mirabilis
>200 μg/mL
MIC
RECORD: Rec_0228069
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus epidermidis
>200 μg/mL
MIC
Showing 5 records on this page · Page 1 of 2