Peptide Database

Peptide NameAngiogenin-4 (EC 3.1.27.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC733H1134N202O206S11

DescriptionStandard

        MTMSPCPLLLVFVLGLVVIPPTLAQNERYEKFLRQHYDAKPNGRDDRYCESMMKERKLTSPCKDVNTFIHGTKKNIRAICGKKGSPYGENFRISNSPFQITTCTHSGASPRPPCGYRAFKDFRYIVIACEDGWPVHFDESFISP
    

Molecular Weight16424.79 Da

Isoelectric Point (pI)9.01

Net Charge (pH 7.0)5.79

Net Charge (pH 7.4) 5.23

Charge Density (pH 7.0) 0.0402

GRAVY Index-0.43

Hydrophobic Moment 0.67

Boman Index-0.05

Instability Index44.56

Aliphatic Index 64.31

Aromaticity 0.1111

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6515.59

LogP -62.22

H-bond Donors 231.0

H-bond Acceptors 227.0

Rotatable Bonds 528.0

Heavy Atoms 1152.0

Ring Count 34.0

Amide Bonds 152.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101484 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyPancreatic ribonuclease

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Endonuclease Hydrolase Nuclease Non-hemolytic

TargetNo Target Organism Found

PaperThe transcriptional landscape of the mammalian genome; Lineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID12548285;16141072;19468303;15489334;17279775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12548285/