Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC230H376N60O70S3

DescriptionStandard

        MAKQKMNLVEIEVMNSLQELTLEELDNVLGAGGGVIQIHFIQTKQW
    

Molecular Weight5198.00 Da

Isoelectric Point (pI)4.70

Net Charge (pH 7.0)-3.40

Net Charge (pH 7.4) -3.68

Charge Density (pH 7.0) -0.0739

GRAVY Index0.02

Hydrophobic Moment 0.40

Boman Index0.15

Instability Index65.88

Aliphatic Index 114.35

Aromaticity 0.0435

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2124.56

LogP -17.05

H-bond Donors 69.0

H-bond Acceptors 71.0

Rotatable Bonds 183.0

Heavy Atoms 363.0

Ring Count 4.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376494 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus sp. oral taxon 431 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria