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MYP_102701
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Basic Information
CXCL14
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide
Immunology ▸ Immune modulation ▸ Cytokine modulation
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Standard
77 amino acids
C418H672N124O112S6
Standard
Sequence
SKCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVIITTKSVSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE
Physicochemical Analysis
9418.96 Da
9.90
12.69
12.23
0.1648
-1.24
0.62
-0.37
46.19
51.82
0.1039
18450.00
18700.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3908.94
-34.39
144.0
134.0
325.0
660.0
17.0
80.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0068274 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID19109182 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19109182/
RECORD: Rec_0189769 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
Propionibacterium spp
1.16 μM
MIC
PaperPotent and broad-spectrum antimicrobial activity of CXCL14 suggests an immediate role in skin infections.
RECORD: Rec_0198497 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
Escherichia coli
0.32 μM
MIC
PaperPotent and broad-spectrum antimicrobial activity of CXCL14 suggests an immediate role in skin infections.
RECORD: Rec_0199085 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
intercrine alpha (chemokine CxC) family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-29; 5-50
Bio-Activity Profile
Cytokine Growth factor intercrine alpha (chemokine CxC) family Chemokine-like
PaperPDB 2HDL structural record; NMR; chain A; residues 1-77
RECORD: Rec_0251221 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
S. coag. neg. spp
1.02 μM
MIC
PaperPotent and broad-spectrum antimicrobial activity of CXCL14 suggests an immediate role in skin infections.
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