Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC367H587N99O88S9

DescriptionStandard

        MKLLLLTLTMLLLLSQLTPGGTQRCWNLYGKCRHRCSKKERVYVYCLNNKMCCVKPKYQPKEKWWPF
    

Molecular Weight8082.78 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.14

Charge Density (pH 7.0) 0.1570

GRAVY Index-0.34

Hydrophobic Moment 0.48

Boman Index-0.07

Instability Index28.72

Aliphatic Index 82.84

Aromaticity 0.1194

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3042.03

LogP -19.28

H-bond Donors 113.0

H-bond Acceptors 109.0

Rotatable Bonds 268.0

Heavy Atoms 563.0

Ring Count 16.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0382535 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence