Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC254H410N82O74S6

DescriptionStandard

        EFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP
    

Molecular Weight5988.87 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.78

Net Charge (pH 7.4) 5.51

Charge Density (pH 7.0) 0.1156

GRAVY Index-1.01

Hydrophobic Moment 0.58

Boman Index-0.39

Instability Index42.03

Aliphatic Index 50.80

Aromaticity 0.1000

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2601.62

LogP -28.06

H-bond Donors 101.0

H-bond Acceptors 86.0

Rotatable Bonds 201.0

Heavy Atoms 416.0

Ring Count 8.0

Amide Bonds 52.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0370900 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide8-36, 15-29, 19-37

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus carnosus TM300

Activity4.5 μg/mL

MethodMIC

FIRST PREV 1 2 3

Showing 1 records on this page Ã‚Â· Page 3 of 3