Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC460H715N127O142S12

DescriptionStandard

        VPDGDFTAQECPECKLKENKYFSKLGAPVYQCAGCCFSRAYPTPVRSQKTMSVPKNVTSESSCCVAKTYTKATVMGNIKVENHTECHCSTCYHHKF
    

Molecular Weight10681.14 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)3.99

Net Charge (pH 7.4) 3.39

Charge Density (pH 7.0) 0.0415

GRAVY Index-0.49

Hydrophobic Moment 0.64

Boman Index-0.07

Instability Index66.87

Aliphatic Index 42.60

Aromaticity 0.0938

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4318.89

LogP -51.48

H-bond Donors 158.0

H-bond Acceptors 162.0

Rotatable Bonds 345.0

Heavy Atoms 741.0

Ring Count 19.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0361095 VERIFIED: YES

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyGlycoprotein hormones

Tax ID37293

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-86; 36-88; 63-91

Other Mods56:N-linked (GlcNAc...) asparagine; 82:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour