‹ ›
MYP_102550
← PREVIOUS NEXT → BACK
Basic Information
Diketopiperazine (GC)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
2 amino acids
C5H10N2O3S
Standard
Sequence
GC
Physicochemical Analysis
178.21 Da
5.52
-0.25
-0.47
-0.1249
1.05
0.26
0.39
5.00
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
92.42
-1.56
4.0
4.0
4.0
11.0
0.0
1.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0077618 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HT-29 (30.56 ± 0.03% Inhibition=10 μM; 51.29 ± 0.01% Inhibition=100 μM)
PMID18436344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18436344/
RECORD: Rec_0097472 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HeLa (43.92 ± 0.02% Inhibition=10 μM ; 57.79 ± 0.02% Inhibition=100 μM)
PMID18436344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18436344/
RECORD: Rec_0295053 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7 (36.49 ± 0.02% Inhibition=10 μM; 56.08 ± 0.01% Inhibition=100 μM)
PMID18436344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18436344/
RECORD: Rec_0296647 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID18436344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18436344/
RECORD: Rec_0303552 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperAi L., Liu L., Zheng L., Liu Y., Sun B., Su G., Xu J., Chen Y., Zhao M.. An on-line stop-flow RPLC ? SEC-MS/DPPH radical scavenging activity analysis system and its application in separation and identification of antioxidant peptides. Food Chem., 436, 137670, 2024.
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2