Peptide Database

Peptide NameDiketopiperazine (GC)

Function Ontology

Anticancer

Antimicrobial

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length2 amino acids

Chemical FormulaC5H10N2O3S

DescriptionStandard

GC

Molecular Weight178.21 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.1249

GRAVY Index1.05

Hydrophobic Moment 0.26

Boman Index0.39

Instability Index5.00

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 92.42

LogP -1.56

H-bond Donors 4.0

H-bond Acceptors 4.0

Rotatable Bonds 4.0

Heavy Atoms 11.0

Ring Count 0.0

Amide Bonds 1.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077618 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetHT-29 cells

Activity30.56±0.03; 51.29±0.01 %

Method% inhibition at 10 μM; 100 μM

RECORD: Rec_0097472 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetHeLa cells

Activity43.92±0.02; 57.79±0.02 %

Method% inhibition at 10 μM; 100 μM

RECORD: Rec_0295053 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetMCF-7 cells

Activity36.49±0.02; 56.08±0.01 %

Method% inhibition at 10 μM; 100 μM

RECORD: Rec_0296647 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0303552 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antioxidant