Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length306 amino acids

Chemical FormulaC1473H2351N405O454S7

DescriptionStandard

        MMAAQARLFTAGKVNIEPGMKMVDLPVRGFITTEDNGRQSVMLVKTGFGSVSATVPVLNGVRDKTTGLDKITVPAVAGAPSRTILVNPVPIGPAAPPHTGNSTPAPVTPVHTGTEVKQADSIVTTTFPAADLPPLQDFIYWQPDVTGTGVEPIYVMLNGPYGETNAKGKYSNRPYNTEKAGGPVQNLDWKAAIIDRAGIDKVKLHTGRFAESDANKVMIDRLEKILKGELQATDTDKRYFTHEVRELERYRQLGVKDSALPANEAEVWNNTHTATLEDYKLGNSETLLYTPEALKAAEEQELRGLK
    

Molecular Weight33222.32 Da

Isoelectric Point (pI)6.02

Net Charge (pH 7.0)-3.02

Net Charge (pH 7.4) -3.58

Charge Density (pH 7.0) -0.0099

GRAVY Index-0.38

Hydrophobic Moment 0.71

Boman Index0.01

Instability Index32.99

Aliphatic Index 81.27

Aromaticity 0.0621

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 29910.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339513 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella michiganensis [Bacterium]

FamilyPyocin/Colicin

Tax ID1134687

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli