Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC185H306N60O59S7

DescriptionStandard

        EFAVCESCKLGRGKCRKECLENEKPDGDCRLNFLCCRER
    

Molecular Weight4539.23 Da

Isoelectric Point (pI)7.80

Net Charge (pH 7.0)0.78

Net Charge (pH 7.4) 0.49

Charge Density (pH 7.0) 0.0200

GRAVY Index-0.83

Hydrophobic Moment 0.46

Boman Index-0.38

Instability Index24.99

Aliphatic Index 50.00

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1978.72

LogP -22.21

H-bond Donors 76.0

H-bond Acceptors 67.0

Rotatable Bonds 159.0

Heavy Atoms 311.0

Ring Count 3.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151517 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Tax ID9600

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0229231 VERIFIED: NO