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MYP_102465
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Basic Information
Unnamed
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Uric acid metabolism ▸ Hypouricemic activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C20H32N6O5
Standard
Sequence
RVY
Physicochemical Analysis
436.51 Da
8.75
0.76
0.55
0.2530
-0.53
1.04
-0.40
-18.47
96.67
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
203.65
-0.76
8.0
6.0
12.0
31.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0161483 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
205.6 μM
IC50
PaperIntegration of QSAR modelling and QM/MM analysis to investigate functional food peptides with antihypertensive activity
RECORD: Rec_0169678 VERIFIED: YES
Provenance & Taxonomy
Actinopterygii [Animal]
7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Angiotensin I-converting enzyme (ACE)
PaperAngiotensin I-converting enzyme inhibitory peptides in an alkaline protease hydrolyzate derived from sardine muscle PMID7765718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7765718/
RECORD: Rec_0213972 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hypouricemic
PaperQi X., Chen H., Guan K., Wang R., Ma Y.. Anti-hyperuricemic and nephroprotective effects of whey protein hydrolysate in potassium oxonate induced hyperuricemic rats. J. Sci. Food Agric., 101, 4916-4924, 2021.
RECORD: Rec_0217265 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
99130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV-2 main protease
PaperViral 3CLpro as a target for antiviral intervention using milk-derived bioactive peptides. International Journal of Peptide Research and Therapeutics 27:2703-2716 (2021). PMID: 34548852. PMID34548852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34548852/
RECORD: Rec_0321901 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
3.69 pIC50
pIC50
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
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