Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length104 amino acids

Chemical FormulaC528H835N147O145S2

DescriptionStandard

        LTAFQLPQKFPLQLRTKNIGVFSPQLQEHYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNTTRVPVFLLNIDANVTGKPTITRNRLGGTVRLTG
    

Molecular Weight11626.31 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)3.11

Net Charge (pH 7.4) 2.67

Charge Density (pH 7.0) 0.0299

GRAVY Index-0.13

Hydrophobic Moment 0.47

Boman Index0.07

Instability Index59.05

Aliphatic Index 96.54

Aromaticity 0.0769

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4640.11

LogP -43.29

H-bond Donors 156.0

H-bond Acceptors 154.0

Rotatable Bonds 369.0

Heavy Atoms 822.0

Ring Count 23.0

Amide Bonds 116.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0403231 VERIFIED: NO

Provenance & Taxonomy

OrganismSmithornis capensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria