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MYP_102458
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Basic Information
Thymosin beta-4 fragment
Cardiovascular
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological regulation
Standard
17 amino acids
C79H131N21O31
Standard
Sequence
PLPSKETIEQEKQAGES
Physicochemical Analysis
1871.01 Da
4.49
-2.03
-2.10
-0.1195
-1.45
0.35
-0.25
101.38
51.76
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
854.25
-10.56
28.0
29.0
65.0
131.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038338 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0048820 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperNeurotoxin-induced neuropeptide perturbations in striatum of neonatal rats PMID23410195 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23410195/
RECORD: Rec_0127079 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
TYB4
10116
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
4:Phosphoserine; 5:N6-acetyllysine; 7:Phosphothreonine; 12:N6-acetyllysine
Bio-Activity Profile
Cardiovascular Growth regulation Development regulation Immunomodulatory
Mammalian: >20 hour; Yeast: >20 hour; E. coli: ?
PaperNeurotoxin-induced neuropeptide perturbations in striatum of neonatal rats PMID23410195 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23410195/
RECORD: Rec_0247730 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0290969 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
TYB4
10116
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
4:Phosphoserine; 5:N6-acetyllysine; 7:Phosphothreonine; 12:N6-acetyllysine
Bio-Activity Profile
Cardiovascular Growth regulation Development regulation Immunomodulatory
the organ
Mammalian: >20 hour; Yeast: >20 hour; E. coli: ?
PaperNeurotoxin-induced neuropeptide perturbations in striatum of neonatal rats PMID23410195 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23410195/