Peptide Database

Peptide NameGallinacin-12 (Gal-12) (Beta-defensin 12) (Gallinacin-10) (Gal-10)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC317H493N87O88S8

DescriptionStandard

        MRNLCFVFIFISLLAHGSTHGPDSCNHDRGLCRVGNCNPGEYLAKYCFEPVILCCKPLSPTPTKT
    

Molecular Weight7187.36 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.21

Charge Density (pH 7.0) 0.0261

GRAVY Index0.06

Hydrophobic Moment 0.65

Boman Index0.10

Instability Index20.27

Aliphatic Index 76.46

Aromaticity 0.0923

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2746.64

LogP -27.04

H-bond Donors 100.0

H-bond Acceptors 101.0

Rotatable Bonds 224.0

Heavy Atoms 500.0

Ring Count 15.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400657 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9031

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic