Peptide Database

Peptide NameRabbit kidney defensin RK-2 (alpha-defensins; lagomorphs, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC175H274N50O45S6

DescriptionStandard

        KPYCSCKWRCGIGEEEKGICHKFPIVTYVCCRRP
    

Molecular Weight3990.75 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)3.79

Net Charge (pH 7.4) 3.44

Charge Density (pH 7.0) 0.1115

GRAVY Index-0.41

Hydrophobic Moment 0.35

Boman Index-0.12

Instability Index66.28

Aliphatic Index 51.47

Aromaticity 0.1176

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1524.32

LogP -12.06

H-bond Donors 60.0

H-bond Acceptors 56.0

Rotatable Bonds 127.0

Heavy Atoms 276.0

Ring Count 9.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370031 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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