MYP_102417
Leuprolide
Anticancer
Hormonal / Endocrine
▸
Hormone peptide
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
XHWSYLLRP
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0053520
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
GnRH analog
32630
Structure & Mods
linear synthetic GnRH analog [Linear]
mixed L/D amino-acid peptide [Mixed]
Pyroglutamate
Ethylamide
D-Leu at position 6
Bio-Activity Profile
Endocrine
GnRH agonist
Hormone therapy
approx. 3 h
RECORD: Rec_0335073
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; synthetic construct [Synthetic]
GnRH
9606;32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Pyroglutamate
N-ethylamide
Non-standard residues/X at 1
Bio-Activity Profile
GnRH agonist
Endocrine
Anticancer
Human GnRH receptor
Clinical/Human: Leuprolide has a terminal elimination half-life of approximately 3 h