Peptide Database

Peptide NameHepcidin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC383H581N89O120S12

DescriptionStandard

        MKTFSVAVAVVVLLAFMSSAVPVTEVLTDPEEPVSYEYEETSAETWMMPFNIGGEQQSGAIKCHFCCSCCAFGVCGTCCTY
    

Molecular Weight8737.01 Da

Isoelectric Point (pI)4.14

Net Charge (pH 7.0)-7.47

Net Charge (pH 7.4) -7.88

Charge Density (pH 7.0) -0.0923

GRAVY Index0.49

Hydrophobic Moment 0.40

Boman Index0.27

Instability Index70.74

Aliphatic Index 68.52

Aromaticity 0.1111

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3261.55

LogP -31.84

H-bond Donors 119.0

H-bond Acceptors 126.0

Rotatable Bonds 273.0

Heavy Atoms 604.0

Ring Count 15.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028721 VERIFIED: NO

Provenance & Taxonomy

OrganismEpinephelus malabaricus [Animal]

FamilyHepcidin

Tax ID162300

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal