Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC430H681N125O135S12

DescriptionStandard

        MKSISVALAVAAAVACLCVLQSEAVPFSQPEVEQQMENEVPQQEQHWTAASAEETRPEEVLFRTKRQSHLSLCRYCCNCCSNKGCGFCCRF
    

Molecular Weight10146.54 Da

Isoelectric Point (pI)5.62

Net Charge (pH 7.0)-2.40

Net Charge (pH 7.4) -2.89

Charge Density (pH 7.0) -0.0264

GRAVY Index-0.14

Hydrophobic Moment 0.57

Boman Index-0.02

Instability Index72.00

Aliphatic Index 66.48

Aromaticity 0.0659

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4197.62

LogP -48.35

H-bond Donors 152.0

H-bond Acceptors 147.0

Rotatable Bonds 334.0

Heavy Atoms 702.0

Ring Count 13.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013235 VERIFIED: NO

Provenance & Taxonomy

OrganismPygocentrus nattereri [Bacterium]

FamilyHepcidin family

Tax ID42514

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence