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MYP_102358
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Basic Information
Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6) (Macrophage activation 2 like protein)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Enzyme / Catalytic activity ▸ Hydrolase
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
611 amino acids
C3132H4974N842O945S28
Standard
Sequence
MTQPQMAPICLVENHNEQLSVNQEAIEILDKISQPVVVVAIVGLYRTGKSYLMNCLAGQNHGFPLGSTVQSQTKGIWMWCMPHPTKPEHTLVLLDTEGLGDVEKGDPKNDLWIFALSVLLSSTFIYNSMITINHQALEQLQYVTELTELIRAKSSPNPAGIKNSTEFVSFFPDFVWTVRDFMLELKLNGEDITSDDYLENALKLIPGDKPRMQASNSCRECIRLFFPNRKCFVFDRPTHDKELLQKLDSITEDQLDPKFQEVTKAFVSYIFTYAKIKTLKEGIKVTGNRLGILVTTYVNAINSGAVPCLDDAVTTLAQRENSVAVQKAADHYSEQMAQRLRLPTETLQELLDVHAACEKEAMAVFMEHSFKDENQQFLKKLVELIGENKELFLSKNEEASNKYCQEELDRLSKDFMENISTFFVPCGHKLYMDKREKIEHDYWQVPRKGVKASEVFQSFLQSQAFIESSILQADTALTAGEKAIAEERAQKVAAEKEQELLRQKQKEQQEYMEAQEKSHKENLEQLRRKLEQEREQDIKDHDMMLKKLMKDQKAFLEEGFKKKAEEMNKEIQQLRDVIKDKKRNTDRIKEALLNGFSTVLFHYLVRYLKHL
Physicochemical Analysis
70441.89 Da
5.74
-12.16
-13.51
-0.0199
-0.49
0.70
-0.07
41.91
85.38
0.0802
49850.00
50475.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0106722 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Mycobacterium bovis (Gram-positive)
PaperLineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID19468303;15489334;18025219;21551061 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19468303/
RECORD: Rec_0236463 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Listeria monocytogenes (Gram-positive)
PaperLineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID19468303;15489334;18025219;21551061 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19468303/
RECORD: Rec_0373532 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Toxoplasma gondii
PaperLineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID19468303;15489334;18025219;21551061 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19468303/