Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC729H1135N183O224S12

DescriptionStandard

        MNLLMLTFMLCGLLTLVTKAGWFVQRCWKNDIGYCRKRCFLIERYKLLCMNKLSCCIPLSSDDPYTQWPIQPPPLEDVTAEFVTQDDIPFTPASGMDDSVTIETTQESTAIRPRSSQISTPTTHESIENTTFSDDLETGYLYKP
    

Molecular Weight16431.68 Da

Isoelectric Point (pI)4.67

Net Charge (pH 7.0)-6.46

Net Charge (pH 7.4) -6.86

Charge Density (pH 7.0) -0.0449

GRAVY Index-0.22

Hydrophobic Moment 0.59

Boman Index0.04

Instability Index44.82

Aliphatic Index 77.85

Aromaticity 0.0972

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6501.39

LogP -61.97

H-bond Donors 230.0

H-bond Acceptors 231.0

Rotatable Bonds 527.0

Heavy Atoms 1148.0

Ring Count 29.0

Amide Bonds 153.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188450 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence