Peptide Database

Peptide NameHBD-3 (22-45)-D [C33,41Del][K45R], [D]HC-3(R)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC106H194N42O31S2

DescriptionStandard

        SCLPKEEQIGKSTRGRKCRRKR
    

Molecular Weight2617.07 Da

Isoelectric Point (pI)10.96

Net Charge (pH 7.0)6.44

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.2928

GRAVY Index-1.82

Hydrophobic Moment 0.34

Boman Index-0.79

Instability Index98.58

Aliphatic Index 35.45

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1257.59

LogP -16.51

H-bond Donors 49.0

H-bond Acceptors 40.0

Rotatable Bonds 96.0

Heavy Atoms 181.0

Ring Count 1.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006870 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans

Activity2.5 μM

MethodMFC

RECORD: Rec_0105884 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetEscherichia coli MG1655[LC = 2.5 microM

RECORD: Rec_0120596 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetStaphylococcus aureus ATCC 8530[LC = 2.5 microM

RECORD: Rec_0260268 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetPseudomonas aeruginosa NCTC 6751[LC = 2.5 microM