‹ ›
MYP_102182
← PREVIOUS NEXT → BACK
Basic Information
Buforin IIb
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C115H207N43O23
Standard
Sequence
RAGLQFPVGRLLRRLLRRLLR
Physicochemical Analysis
2560.15 Da
12.00
6.76
6.56
0.3219
-0.10
1.11
-0.34
117.82
148.57
0.0476
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1112.92
-7.79
43.0
30.0
88.0
181.0
2.0
21.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0325219 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
P. putida
2 μg/mL
MIC
PMID22306477 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22306477/
RECORD: Rec_0327696 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. mutans
2 μg/mL
MIC
PMID22306477 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22306477/
RECORD: Rec_0335168 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Histone H2A-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
BT-549
12.9 μg/mL
IC50
PaperMechanism of anticancer activity of buforin IIb, a histone H2A-derived peptide PMID18617323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18617323/
RECORD: Rec_0341969 VERIFIED: NO
Provenance & Taxonomy
Bufo gargarizans [Animal]
Buforin
30331.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0344039 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
1 μg/mL
MIC
PMID22306477 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22306477/
FIRST PREV 1 ... 10 11 12 13 14 ... 16 NEXT LAST
Showing 5 records on this page · Page 12 of 16