MYP_102182
Basic Information
Buforin IIb
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Delivery / Targeting Cell penetration Cell-penetrating peptide
Delivery / Targeting Drug delivery vehicle
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
Standard
21 amino acids
C115H207N43O23
Standard
Sequence
RAGLQFPVGRLLRRLLRRLLR
Physicochemical Analysis
2560.15 Da
12.00
6.76
6.56
0.3219
-0.10
1.11
-0.34
117.82
148.57
0.0476
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1112.92
-7.79
43.0
30.0
88.0
181.0
2.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0278487 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Histone H2A-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
PC-3
12 μg/mL
IC50
RECORD: Rec_0279347 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Histone H2A-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
MDA-MB-231
11.3 μg/mL
IC50
RECORD: Rec_0290414 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Histone H2A-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
SK-MEL-2
11.1 μg/mL
IC50
RECORD: Rec_0300352 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Histone H2A-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
NCI-H460
12.1 μg/mL
IC50
RECORD: Rec_0300736 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Histone H2A-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
SNB-19
13.8 μg/mL
IC50
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