Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC360H577N93O94S8

DescriptionStandard

        MKVLLSLLGVLALLSIVPQARSLFFQEGCPSGYYNCRMKCNANEYAVKYCADWTICCKEKKKVKEKKKW
    

Molecular Weight7968.52 Da

Isoelectric Point (pI)9.36

Net Charge (pH 7.0)7.44

Net Charge (pH 7.4) 7.11

Charge Density (pH 7.0) 0.1078

GRAVY Index-0.12

Hydrophobic Moment 0.38

Boman Index-0.01

Instability Index25.82

Aliphatic Index 84.78

Aromaticity 0.1159

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3050.16

LogP -21.69

H-bond Donors 112.0

H-bond Acceptors 110.0

Rotatable Bonds 271.0

Heavy Atoms 555.0

Ring Count 12.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037251 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

FamilyDefensin

Tax ID30522

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0178581 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus grunniens (Wild yak) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin