Peptide Database

Peptide NameCathelicidin-1 (Bactenecin-1) (Bac1) (Cyclic dodecapeptide)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length155 amino acids

Chemical FormulaC765H1240N228O234S7

DescriptionStandard

        METPRASLSLGRWSLWLLLLGLALPSASAQALSYREAVLRAVDQLNEQSSEPNIYRLLELDQPPQDDEDPDSPKRVSFRVKETVCSRTTQQPPEQCDFKENGLLKRCEGTVTLDQVRGNFDITCNNHQSIRITKQPWAPPQAARLCRIVVIRVCR
    

Molecular Weight17599.87 Da

Isoelectric Point (pI)7.58

Net Charge (pH 7.0)0.56

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0036

GRAVY Index-0.50

Hydrophobic Moment 0.66

Boman Index-0.13

Instability Index49.92

Aliphatic Index 88.06

Aromaticity 0.0516

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7503.27

LogP -80.80

H-bond Donors 263.0

H-bond Acceptors 243.0

Rotatable Bonds 580.0

Heavy Atoms 1234.0

Ring Count 24.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413226 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCathelicidin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)