MYP_102141
Fusaricidin B
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antifungal
Standard
6 amino acids
C26H47N7O10
Standard
TVVTQA
617.69 Da
5.18
-0.60
-0.79
-0.1003
0.88
0.41
0.30
-18.38
113.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
292.37
-3.82
10.0
10.0
18.0
43.0
0.0
6.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0025324
VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Gln5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). Refer to the article for additional physical properties
Bio-Activity Profile
Antimicrobial
Antifungal
Gram-positive Staphylococcus aureus FDA 209p, Staphylococcus aureus Smith, Micrococcus luteus IFO 3333, Bacillus subtilis ATCC 6633
1.56-6.25 μg/mL
MIC
RECORD: Rec_0049945
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0135390
VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Gln5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). Refer to the article for additional physical properties
Bio-Activity Profile
Antimicrobial
Antifungal
Inactive: Escherichia coli NIHJ, Klebsiella pneumoniae KC-1, Pseudomonas aeruginosa IFO 3445, S.marcescens IFO 3736
>100 μg/mL
MIC
RECORD: Rec_0224645
VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Gln5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). Refer to the article for additional physical properties
Bio-Activity Profile
Antimicrobial
Antifungal
fungi Fusarium oxysporum HF8801, Fusarium oxysporum HF8835, A. niger HUT 2016, A. oryzae 1FO 4214, P. thomii
1.56-3.12 μg/mL
MIC
RECORD: Rec_0291851
VERIFIED: YES
Provenance & Taxonomy
Paenibacillus polymyxa [Bacterium]; Bacteria [Bacterium]
1405; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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