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MYP_102137
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Basic Information
Avian beta-defensin 6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
67 amino acids
C342H531N97O83S7
Standard
Sequence
MRILYLLLSVLFVVLQGVAGQPYFSSPIHACRYQRGVCIPGPCRWPYYRVGSCGSGLKSCCVRNRWA
Physicochemical Analysis
7553.93 Da
9.69
7.52
7.16
0.1123
0.31
0.51
0.13
55.31
92.99
0.1343
18450.00
18825.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2854.44
-22.97
109.0
99.0
233.0
529.0
17.0
70.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004114 VERIFIED: YES
Provenance & Taxonomy
Anas platyrhynchos [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pasteurella multocida ATCC 6529
PMID23112840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23112840/
RECORD: Rec_0031628 VERIFIED: NO
Provenance & Taxonomy
Anser cygnoides [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ4976
RECORD: Rec_0053901 VERIFIED: YES
Provenance & Taxonomy
Anas platyrhynchos [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella choleraesuis CVCC 2140
PMID23112840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23112840/
RECORD: Rec_0071307 VERIFIED: YES
Provenance & Taxonomy
Anas platyrhynchos [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Duck erythrocytes
Hemolysis
PMID23112840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23112840/
RECORD: Rec_0082833 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Beta-defensin; Defensin
9031
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Non-hemolytic
Salmonella Typhimurium
PMID15148642;15310403;17346671;17244739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15148642/
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