Peptide Database

Peptide NameCathelicidin-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC323H526N110O60

DescriptionStandard

        RRIRPRPPRLPRPRPRPLPFPRPGPRPIPRPLPFPRPGPRPIPRPLPFPRPGPRPIPRP
    

Molecular Weight6910.33 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)16.76

Net Charge (pH 7.4) 16.56

Charge Density (pH 7.0) 0.2841

GRAVY Index-1.37

Hydrophobic Moment 0.80

Boman Index-0.42

Instability Index81.79

Aliphatic Index 52.88

Aromaticity 0.0508

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2557.30

LogP -17.84

H-bond Donors 83.0

H-bond Acceptors 77.0

Rotatable Bonds 179.0

Heavy Atoms 493.0

Ring Count 31.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0362070 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Familycathelicidin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans ATCC 37092

Activity0.26 μM

MethodMIC

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