Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC563H885N161O158S9

DescriptionStandard

        LPFVLLLSFFPPIFNLIPEYLLSFEMIFCGGQKSCWIIKGHCRKNCKSGEQVKKPCKNGDYCCIPSKTNSQPHRPTQPLTRRCRTVSTNSERNDVSEHVAFSHHKTSKNLE
    

Molecular Weight12725.62 Da

Isoelectric Point (pI)9.26

Net Charge (pH 7.0)8.13

Net Charge (pH 7.4) 7.52

Charge Density (pH 7.0) 0.0732

GRAVY Index-0.50

Hydrophobic Moment 0.69

Boman Index-0.09

Instability Index36.18

Aliphatic Index 66.67

Aromaticity 0.0901

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5132.76

LogP -53.83

H-bond Donors 183.0

H-bond Acceptors 180.0

Rotatable Bonds 417.0

Heavy Atoms 891.0

Ring Count 25.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404771 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus americanus [Animal]

FamilyDefensin

Tax ID9643

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence