MYP_102106
NBC2253 (De Novo Synthesis)
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
▸
Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
▸
Anti-Gram-positive
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
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General toxin
▸
Cytotoxic
Standard
17 amino acids
C91H163N23O21S
Standard
CGIYRSLKLIKSLVLIK
1947.47 Da
10.03
3.75
3.52
0.2204
0.94
0.64
0.18
0.34
177.65
0.0588
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
729.57
-2.72
28.0
26.0
69.0
136.0
1.0
16.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0375266
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Methicillin Resistant Staphylococcus aureus (methicillin-resistant Staphylococcus aureus)
6.7±0.02 μM
MIC50
RECORD: Rec_0376371
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
The sulfhydryl side chain of the cysteine residue was conjugated to AuNC(previously modified with SPDP) via a disulfide bond.
None
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
bovine blood cells
RECORD: Rec_0379392
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
The sulfhydryl side chain of the cysteine residue was conjugated to AuNC(previously modified with SPDP) via a disulfide bond.
None
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Cytotoxic
The cell viability of Vero ATCC CCL 1-81 cells induced by NBC2253 is 87
RECORD: Rec_0384572
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
The sulfhydryl side chain of the cysteine residue was conjugated to AuNC(previously modified with SPDP) via a disulfide bond.
None
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Cytotoxic
Showing 4 records on this page · Page 2 of 2