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MYP_102079
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Basic Information
Cholecystokinin-8
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
8 amino acids
C49H61N9O14S2
Standard
Sequence
DYMGWMDF
Physicochemical Analysis
1064.19 Da
4.05
-2.24
-2.44
-0.2798
-0.38
0.13
0.28
99.28
0.00
0.3750
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
377.64
-0.21
13.0
14.0
31.0
74.0
4.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0192092 VERIFIED: YES
Provenance & Taxonomy
Macropus giganteus [Animal]
Cholecystokinin
9317
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
2:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Myotropic Receptor modulation
CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Experimental: 18 minute; /1080 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Cholecystokinin (Macropus giganteus): PMID 8134294##6291099 PMID8134294;6291099 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8134294/
RECORD: Rec_0202254 VERIFIED: YES
Provenance & Taxonomy
Calliphora vomitoria [Animal]
Gastrin/cholecystokinin
27454
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Tyr2 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID8118842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8118842/
RECORD: Rec_0214908 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Cholecystokinin
8355
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
2:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator
Experimental: 18 minute; /1080 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperDegradation of cholecystokinin octapeptide, related fragments and analogs by human and rat plasma in vitro PMID6291099 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6291099/
RECORD: Rec_0222209 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Cholecystokinin
9031
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
2:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Myotropic Feeding regulator
Experimental: 18 minute; /1080 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Cholecystokinin-8 (Gallus gallus): PMID 3620999##6291099 PMID3620999;6291099 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3620999/
RECORD: Rec_0240082 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Cholecystokinin
9615
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
2:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation
Experimental: 18 minute; /1080 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Cholecystokinin-8 (Canis lupus familiaris): PMID 2430967##6291099 PMID2430967;6291099 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2430967/
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