Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length187 amino acids

Chemical FormulaC909H1417N265O236S11

DescriptionStandard

        PAALPVAHEPMLLVAVTELVATSAASVYFTAGALRRNITGSMVGTGRLRSWGRAVPRACPQLQERYPDQPMELRLWARRQPWVSCRPDALHGTMAGAAEAFVVLPNATRVPAFLLDIWPRWGHNGVARGVPVLCIPPGAGGWGGCDPRAGLRGACPQVQRLETLLKFGLWLFGVPWANSECCPHPVP
    

Molecular Weight20186.32 Da

Isoelectric Point (pI)9.49

Net Charge (pH 7.0)7.26

Net Charge (pH 7.4) 6.88

Charge Density (pH 7.0) 0.0388

GRAVY Index0.08

Hydrophobic Moment 0.88

Boman Index0.12

Instability Index58.63

Aliphatic Index 87.17

Aromaticity 0.0802

Extinction Coeff. Reduced 46980.00

Extinction Coeff. Oxidized 47355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7770.37

LogP -82.15

H-bond Donors 276.0

H-bond Acceptors 258.0

Rotatable Bonds 614.0

Heavy Atoms 1421.0

Ring Count 48.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0396412 VERIFIED: NO

Provenance & Taxonomy

OrganismSyrrhaptes paradoxus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria