Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length459 amino acids

Chemical FormulaC2328H3685N629O649S11

DescriptionStandard

        TNPGFVVRITQTGLDYAQEQGIAILEKELAQLKLPDISGNSRVLRVGKVHYELSRLRLRDFHLPYSRITPISNMGLQVSISNAFAELDGDWRVKFLFIRDHGSFNLKVENIYIKILLRLGSDTTGKPTISSPDCSARISKVRVLFSGKLGWLYNLFHSVIESRLRRILENKVCDNVAKSVHNELQTYIQTLPVTARIDDKIGVDYSLVAPPRATPKSLDADLKGEFYSLAHRSPVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEITEAMIPKDVEFKLDTSVFSAFIPQLEEMYPNMPMKFRLSTPTAPFLTIGPGGISFQPIVDVQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRYRGQQPLPGQGGAGDFSVRMMQSLMNILTSSTLLPRLNARLDEGFPLPLLDRIQLSNILVRFHQNFLLLGADVRFQPR
    

Molecular Weight51221.70 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)10.20

Net Charge (pH 7.4) 9.44

Charge Density (pH 7.0) 0.0222

GRAVY Index0.02

Hydrophobic Moment 0.70

Boman Index0.08

Instability Index38.31

Aliphatic Index 102.57

Aromaticity 0.0937

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0235877 VERIFIED: NO

Provenance & Taxonomy

OrganismRhodinocichla rosea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria