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MYP_102007
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Basic Information
Temporin-1Vc
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C75H122N14O15S
Standard
Sequence
FLPLVTMLLGKLF
Physicochemical Analysis
1491.92 Da
8.75
0.76
0.55
0.0584
1.85
0.32
0.65
4.45
172.31
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
449.98
1.99
15.0
17.0
47.0
105.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0089978 VERIFIED: YES
Provenance & Taxonomy
Rana virgatipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (MRSA) T7/20
10 μM
MIC
PMID15996769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15996769/
RECORD: Rec_0104013 VERIFIED: YES
Provenance & Taxonomy
Rana virgatipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID15996769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15996769/
RECORD: Rec_0119286 VERIFIED: YES
Provenance & Taxonomy
Lithobates virgatipes [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
30.0 μM
HC50
PaperJ.M. Conlon et al. / Regulatory Peptides 131 (2005) 38-45. Purification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana)
RECORD: Rec_0138614 VERIFIED: YES
Provenance & Taxonomy
Rana virgatipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
C-terminal amidation
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa ATCC 27853
160 μM
MIC
PaperPurification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana).
RECORD: Rec_0150418 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
30 μM
LD50
Paperhttps://pubmed.ncbi.nlm.nih.gov/15996769/ PMID15996769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15996769/
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